Description

(R)-2-Methyl-1-(4-Methylphenylsulfonamido)-1-Phenylpropan-2-Yl 2,4,6-Triisopropylbenzenesulfinate is a high-purity chiral sulfinate ester, a crucial class of intermediates in modern asymmetric synthesis. This compound matters because it serves as a versatile chiral auxiliary or ligand precursor, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research and development chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures with high stereoselectivity. The CAS number for this compound is 1957130-66-3.

Application

• As a chiral auxiliary in asymmetric carbon-carbon and carbon-heteroatom bond-forming reactions.
• As a precursor for the synthesis of chiral sulfoxides, which are valuable ligands in transition metal catalysis.
• In the research and development of enantiomerically pure active pharmaceutical ingredients (APIs) for central nervous system, cardiovascular, and oncological therapies.
• For the preparation of advanced intermediates in agrochemical and specialty chemical synthesis.
• As a key building block in methodological studies for new asymmetric transformations in academic and industrial laboratories.
• In process chemistry for the scale-up and optimization of stereoselective synthetic routes.

Basic Information

Product Name	(R)-2-Methyl-1-(4-Methylphenylsulfonamido)-1-Phenylpropan-2-Yl 2,4,6-Triisopropylbenzenesulfinate
CAS No.	1957130-66-3
Molecular Formula	C29H37NO4S2
Molecular Weight	527.73 g/mol
Synonyms	(R)-2-Methyl-1-[(4-methylphenyl)sulfonyl]amino-1-phenylpropan-2-yl 2,4,6-triisopropylbenzenesulfinate; (R)-N-[(2-Hydroxy-1,1-dimethyl-2-phenylethyl)-4-methylbenzenesulfonamido] 2,4,6-triisopropylbenzenesulfinate; Chiral Sulfinate Ester 1957130-66-3; (R)-TsNHP-Sulfinate Ester; (R)-Methylphenylsulfonamido Phenylpropanol Triisopropylbenzenesulfinate
EINECS	Contact for details

Quality Control

Our (R)-2-Methyl-1-(4-Methylphenylsulfonamido)-1-Phenylpropan-2-Yl 2,4,6-Triisopropylbenzenesulfinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.