Description

(S)-2-Aminobut-3-Ynoic Acid Hcl is a chiral, non-proteinogenic amino acid derivative featuring an alkyne functional group. This unique structural motif makes it a valuable building block for the synthesis of complex molecules in medicinal chemistry and chemical biology. It is primarily sought after by researchers and manufacturers in the pharmaceutical and biotechnology sectors for developing novel therapeutics and probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Peptidomimetics & Conjugation: Used to incorporate alkyne handles into peptides and proteins for subsequent bioorthogonal conjugation (e.g., via Click Chemistry) in drug delivery systems and diagnostic agents.
• Chemical Biology Probes: Serves as a precursor for synthesizing activity-based probes and molecular tools to study enzyme function and biological pathways.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and asymmetric synthesis.
• Agrochemical Research: Potential intermediate in the development of novel, high-performance crop protection agents.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis and material science.

Basic Information

Item	Details
Product Name	(S)-2-Aminobut-3-Ynoic Acid Hcl
CAS No.	1956434-80-2
Molecular Formula	C4H6ClNO2
Molecular Weight	135.55 g/mol
Synonyms	(S)-2-Amino-3-butynoic acid hydrochloride; (S)-2-Amino-but-3-ynoic acid hydrochloride; (S)-2-Amino-3-butynoic acid HCl; (S)-2-Amino-but-3-ynoic acid HCl; (S)-2-Amino-3-butynoate hydrochloride; (S)-Ethynylglycine hydrochloride; (S)-2-Amino-3-butynoic acid monohydrochloride
EINECS	Contact for details

Quality Control

Our (S)-2-Aminobut-3-Ynoic Acid Hcl is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric excess, meeting the stringent requirements for research and development. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.