Description

5-(Methylsulfonyl)Quinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its quinoline core functionalized with both a methylsulfonyl and a carboxylic acid group. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for oncology, anti-inflammatory, and central nervous system (CNS) targets.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Organic Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its reactive carboxylic acid and electron-withdrawing sulfone moiety.
• Agrochemical Research: Employed in the development of new herbicides and fungicides, where the quinoline structure can contribute to biological activity.
• Material Science: Investigated as a monomer or functional component in the creation of specialty polymers and advanced organic electronic materials.
• Contract Research & Development (CRO/CMO): Supplied to organizations providing custom synthesis and process scale-up services for the life sciences industry.

Basic Information

Product Name	5-(Methylsulfonyl)Quinoline-3-Carboxylic Acid
CAS No.	1956383-11-1
Molecular Formula	C11H9NO4S
Molecular Weight	251.26 g/mol
Synonyms	3-Quinolinecarboxylic acid, 5-(methylsulfonyl)-; 5-Methanesulfonylquinoline-3-carboxylic acid; 5-(Methylsulfonyl)-3-quinolinecarboxylic acid; Quinoline-3-carboxylic acid, 5-(methylsulfonyl)-; 5-Mesylquinoline-3-carboxylic acid; 1956383-11-1; 5-(Methylsulfonyl)quinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our production of 5-(Methylsulfonyl)Quinoline-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up work. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment. We support development under cGMP guidelines as required for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.