Description

4-Bromo-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is critical for medicinal chemistry and agrochemical research, serving as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and crop protection agents. It is primarily utilized by R&D scientists and process chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce bromine and trifluoromethyl-substituted pyrazolopyridine scaffolds into their molecular targets.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing potential drug candidates, particularly in kinase inhibitor research and the development of treatments for oncology and inflammatory diseases.
• Agrochemical Research: Used in the discovery and synthesis of new herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrazolopyridine core.
• Material Science Precursor: Serves as a specialized monomer or ligand in the development of advanced organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probe: Employed in the design of molecular probes and tags for studying biological pathways and protein functions due to its distinct structural features.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	4-Bromo-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine
CAS No.	1956382-83-4
Molecular Formula	C7H3BrF3N3
Molecular Weight	266.02 g/mol
Synonyms	4-Bromo-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine, 4-bromo-3-(trifluoromethyl)-; 4-Bromo-3-trifluoromethyl-1H-pyrazolo[3,4-b]pyridine; 1956382-83-4; 4-Bromo-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine; 4-Bromo-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and development. Our quality assurance protocol includes identity confirmation, purity assay, and impurity profiling via advanced chromatographic and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should be performed under subdued lighting or amber glass containers to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.