Description

3-Bromo-2-Ethynylquinoline is a high-value, multi-functional heterocyclic building block characterized by its bromine and ethynyl substituents on the quinoline core. This compound is essential for advanced organic synthesis, particularly in the construction of complex molecular architectures via cross-coupling and cycloaddition reactions. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for kinase inhibitors and other biologically active quinoline derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science: Serves as a monomer or building block for creating organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Synthesis: Enables Sonogashira, Suzuki-Miyaura, and other palladium-catalyzed cross-coupling reactions to introduce complex alkynyl groups.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and the exploration of new reaction pathways.
• Ligand Synthesis: Used to prepare novel nitrogen-containing ligands for catalysis and coordination chemistry.

Basic Information

Item	Detail
Product Name	3-Bromo-2-Ethynylquinoline
CAS No.	1956382-34-5
Molecular Formula	C11H6BrN
Molecular Weight	232.08 g/mol
Synonyms	2-Ethynyl-3-bromoquinoline; 3-Bromo-2-ethynylquinoline; Quinoline, 3-bromo-2-ethynyl-; 2-(Ethynyl)-3-bromoquinoline
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Ethynylquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.