Description

3-Bromoquinoline-6-Sulfonyl Chloride is a high-purity, multi-functional organic building block essential for advanced chemical synthesis. Its core value lies in its dual reactive sites—the sulfonyl chloride and bromo substituent—which enable precise, sequential derivatization to create complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel quinoline-based active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors, antiviral agents, and other biologically active quinoline derivatives.
• Agrochemical Research: Building block for developing new generation herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science: Used in the creation of organic semiconductors, light-emitting materials, and metal-organic frameworks (MOFs) due to its electron-deficient quinoline core.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling proteins, creating activity-based probes (ABPs), and developing covalent inhibitors.
• Dye & Pigment Synthesis: Intermediate for producing specialized quinoline-based dyes, fluorescent tags, and photostable colorants.
• Cross-Coupling Reactions: The bromo group serves as a versatile handle for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira), enabling rapid library synthesis.

Basic Information

Product Name	3-Bromoquinoline-6-Sulfonyl Chloride
CAS No.	1956381-95-5
Molecular Formula	C9H5BrClNO2S
Molecular Weight	306.56 g/mol
Synonyms	6-(Chlorosulfonyl)-3-bromoquinoline; 3-Bromo-6-quinolinesulfonyl chloride; Quinoline, 3-bromo-6-sulfonyl chloride; 3-Bromoquinoline-6-sulfonchlorid; 1956381-95-5; 3-Br-6-SO2Cl-Quinoline
EINECS	Contact for details

Quality Control

Our 3-Bromoquinoline-6-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Standard quality checks include HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use. Recommended long-term storage temperature is 2-8°C. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.