Description

Quinazoline, 7-Bromo-5-Fluoro-2-Iodo- is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which enables the construction of complex molecules with tailored electronic and steric properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, particularly in medicinal chemistry programs targeting kinase inhibition and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Kinase Inhibitor Scaffold: Serves as a privileged core structure for designing and synthesizing potent and selective kinase inhibitors.
• Agrochemical Research: Used in the discovery of new herbicides, fungicides, and insecticides due to its bioactive quinazoline core.
• Material Science Precursor: Potential building block for organic electronic materials, such as OLEDs or semiconductors, leveraging its halogenated structure.
• Chemical Biology Probe: Employed in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the cGMP and non-GMP production of complex target molecules.

Basic Information

Product Name	Quinazoline, 7-Bromo-5-Fluoro-2-Iodo-
CAS No.	1956380-63-4
Molecular Formula	C8H3BrFIN2
Molecular Weight	352.93 g/mol
Synonyms	7-Bromo-5-fluoro-2-iodoquinazoline; 2-Iodo-7-bromo-5-fluoroquinazoline; 5-Fluoro-7-bromo-2-iodoquinazoline; Quinazoline, 7-bromo-5-fluoro-2-iodo-; 1956380-63-4; 7-Br-5-F-2-I-quinazoline
EINECS	Contact for details

Quality Control

Every batch of 7-Bromo-5-Fluoro-2-Iodoquinazoline is manufactured under strict quality management systems. We provide comprehensive analytical documentation to support your research and regulatory filings. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.