Description

cis-3-Fluorocyclopentan-1-Amine Hydrochloride is a high-purity, synthetically valuable chiral amine building block. This compound is essential for medicinal chemistry research and development, serving as a key intermediate in the creation of novel pharmaceutical candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce a fluorinated cyclopentylamine motif into target molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the impact of fluorination on a cyclopentane scaffold.
• Agrochemical Development: Serves as a building block for novel active ingredients in crop protection products.
• Ligand Synthesis: Employed in the preparation of chiral ligands for asymmetric catalysis.
• Peptidomimetics: Incorporated into peptide analogs to enhance metabolic stability and binding affinity.
• Chemical Biology Probes: Used to develop tool compounds for studying biological targets and pathways.

Basic Information

Product Name	cis-3-Fluorocyclopentan-1-Amine Hydrochloride
CAS No.	1956377-21-1
Molecular Formula	C5H11ClFN
Molecular Weight	139.60 g/mol (Free base: 103.15 g/mol)
Synonyms	cis-3-Fluorocyclopentylamine Hydrochloride; (1R,3S)-3-Fluorocyclopentan-1-amine Hydrochloride; (1S,3R)-3-Fluorocyclopentan-1-amine Hydrochloride; 3-Fluorocyclopentanamine Hydrochloride, cis-; 1-Amino-3-fluorocyclopentane Hydrochloride; 3-Fluoro-1-cyclopentanamine Hydrochloride; FCyclopentNH2·HCl; 1956377-21-1
EINECS	Contact for details

Quality Control

Our cis-3-Fluorocyclopentan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.