Description

3-Chloroquinoline-7-Sulfonyl Chloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. This compound is valued for its dual reactive sites, the chloroquinoline and sulfonyl chloride groups, which enable precise derivatization and the construction of complex molecular architectures. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, including the synthesis of potential drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, particularly for targeting infectious diseases and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides that require the quinoline scaffold for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the creation of specialty polymers and functional materials.
• Dye and Pigment Manufacturing: Employed in the synthesis of complex heterocyclic dyes and organic pigments.
• Chemical Biology Probes: Utilized to create sulfonamide-linked probes for studying enzyme function and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical reagent for fine chemical producers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	3-Chloroquinoline-7-Sulfonyl Chloride
CAS No.	1956371-35-9
Molecular Formula	C9H5Cl2NO2S
Molecular Weight	278.11 g/mol
Synonyms	7-Chlorosulfonyl-3-chloroquinoline; 3-Chloro-7-quinolinesulfonyl chloride; Quinoline-7-sulfonyl chloride, 3-chloro-; 3-Chloroquinoline-7-sulfonic acid chloride; 1956371-35-9; 3,7-Dichloroquinoline Sulfone Derivative
EINECS	Contact for details

Quality Control

Every batch of 3-Chloroquinoline-7-Sulfonyl Chloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.