Description

1-(3-Chloro-2-Fluorophenyl)Ethan-1-Amine Hydrochloride is a high-purity, synthetically derived organic salt of significant value in advanced chemical synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily required by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Academic and R&D: Utilized in university and corporate research laboratories for methodological studies and exploring new chemical entities.
• Custom Synthesis Building Block: Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects requiring specific fluorinated and chlorinated aromatic amines.

Basic Information

Product Name	1-(3-Chloro-2-Fluorophenyl)Ethan-1-Amine Hydrochloride
CAS No.	1956371-30-4
Molecular Formula	C8H10Cl2FN
Molecular Weight	210.08 g/mol
Synonyms	1-(3-Chloro-2-fluorophenyl)ethanamine hydrochloride; α-Methyl-3-chloro-2-fluoro-benzenemethanamine hydrochloride; (1-(3-Chloro-2-fluorophenyl)ethyl)amine hydrochloride; 3-Chloro-2-fluoro-α-methylbenzylamine hydrochloride; 1-(3-Chloro-2-fluorophenyl)ethylamine HCl; 1-Amino-1-(3-chloro-2-fluorophenyl)ethane hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3-Chloro-2-Fluorophenyl)Ethan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.