Description

6-(Methylsulfonyl)Quinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its quinoline core functionalized with both a methylsulfonyl and a carboxylic acid group. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel, biologically active molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating potential drug candidates targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: The quinoline-sulfonyl motif is valuable for constructing potential inhibitors targeting various kinase enzymes involved in disease pathways.
• Chemical Biology Probes: Serves as a starting material for developing molecular probes to study biological processes and identify new drug targets.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	6-(Methylsulfonyl)Quinoline-3-Carboxylic Acid
CAS No.	1956366-84-9
Molecular Formula	C₁₁H₉NO₄S
Molecular Weight	251.26 g/mol
Synonyms	6-(Methanesulfonyl)quinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 6-(methylsulfonyl)-; 6-Methylsulfonylquinoline-3-carboxylic acid; Quinoline-3-carboxylic acid, 6-(methylsulfonyl)-; 1956366-84-9; 6-(Methylsulfonyl)-3-quinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 6-(Methylsulfonyl)Quinoline-3-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Our quality systems support delivery under current Good Manufacturing Practice (cGMP) guidelines for advanced intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.