Description

3-Chloroquinoline-5-Sulfonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive sulfonyl chloride and chlorinated quinoline moieties. This compound is essential for introducing the 3-chloroquinoline-5-sulfonyl group into target molecules, enabling the synthesis of complex structures with tailored properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients, as well as by specialty chemical manufacturers developing advanced materials and ligands.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry research targeting various disease pathways.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactive quinoline scaffold.
• Material Science Research: Serves as a precursor for creating functionalized polymers, dyes, and advanced organic materials.
• Chemical Biology & Proteomics: Can be utilized to develop activity-based probes or affinity tags for studying enzyme function and protein interactions.
• Ligand Synthesis for Catalysis: Acts as a starting material for synthesizing novel quinoline-based ligands used in metal-catalyzed reactions.

Basic Information

Product Name	3-Chloroquinoline-5-Sulfonyl Chloride
CAS No.	1956366-76-9
Molecular Formula	C9H5Cl2NO2S
Molecular Weight	278.11 g/mol
Synonyms	3-Chloro-5-quinolinesulfonyl chloride; Quinoline-5-sulfonyl chloride, 3-chloro-; 5-(Chlorosulfonyl)-3-chloroquinoline; 3-Chloroquinoline-5-sulfonylchloride; 1956366-76-9; 3-Chloro-quinoline-5-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Chloroquinoline-5-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to reliable supply and batch-to-batch consistency meets the stringent requirements of advanced R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.