Description

3-Bromo-5-(Methylsulfonyl)Quinoline is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its unique quinoline core functionalized with bromo and methylsulfonyl groups makes it a critical precursor for constructing complex molecules with tailored biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides with specific modes of action.
• Material Science: Serves as a precursor for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport layers.
• Chemical Synthesis: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization due to the reactive bromine atom.
• Ligand & Catalyst Development: Used to synthesize complex ligands for catalysis and metal-organic frameworks (MOFs).
• Life Science Research: Employed in biochemical research as a probe or scaffold for studying protein interactions and cellular pathways.

Basic Information

Product Name	3-Bromo-5-(Methylsulfonyl)Quinoline
CAS No.	1956366-71-4
Molecular Formula	C₁₁H₈BrNO₂S
Molecular Weight	298.16 g/mol
Synonyms	3-Bromo-5-(methylsulfonyl)quinoline; 5-(Methylsulfonyl)-3-bromoquinoline; Quinoline, 3-bromo-5-(methylsulfonyl)-; 3-Bromo-5-methanesulfonylquinoline; 1956366-71-4
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(Methylsulfonyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC, NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.