Description

5-(Trifluoromethyl)-2H-Spiro[Benzofuran-3,4-Piperidine] (Wxc00093) is a high-value, fluorinated spirocyclic compound that serves as a sophisticated building block in advanced organic synthesis. Its unique molecular architecture, featuring a benzofuran ring fused to a piperidine moiety with a trifluoromethyl group, makes it a critical intermediate for modulating the physicochemical and pharmacological properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) disorders, due to its spirocyclic and fluorinated structure.
• Agrochemical Synthesis: Used in the design and synthesis of advanced pesticides and herbicides, where the trifluoromethyl group often enhances biological activity and environmental stability.
• Material Science Research: Employed as a building block for developing novel organic electronic materials or specialty polymers with tailored properties.
• Medicinal Chemistry Scaffold: Serves as a privileged scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Chemical Biology Probe: Utilized in the development of molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, fluorinated heterocyclic frameworks.

Basic Information

Item	Details
Product Name	5-(Trifluoromethyl)-2H-Spiro[Benzofuran-3,4-Piperidine] (Wxc00093)
CAS No.	1956364-67-2
Molecular Formula	C13H12F3NO
Molecular Weight	255.24 g/mol
Synonyms	5-(Trifluoromethyl)-2H-spiro[benzofuran-3,4'-piperidine]; 2H-Spiro[benzofuran-3,4'-piperidine], 5-(trifluoromethyl)-; WXC-00093; WXC00093; 5-Trifluoromethylspiro[benzofuran-3,4-piperidine]; 5-(Trifluoromethyl)spiro[benzofuran-3,4'-piperidine]; Spiro[benzofuran-3,4'-piperidine], 5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 5-(Trifluoromethyl)-2H-Spiro[Benzofuran-3,4-Piperidine] is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and full spectroscopic data is provided with each shipment to support your R&D and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.