Description

1-Oxa-6-Azaspiro[3.4]Octane Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value in modern drug discovery, particularly for its role as a key building block in the synthesis of novel, bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including potential candidates for neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Proteolysis Targeting Chimera (PROTAC) Development: Used as a component in the linker or warhead design for targeted protein degradation therapeutics.
• Covalent Inhibitor Synthesis: The spirocyclic structure can be functionalized to create selective covalent inhibitors for challenging drug targets.
• Chemical Biology Probes: Employed in the development of tool compounds for investigating biological pathways and target validation.

Basic Information

Product Name	1-Oxa-6-Azaspiro[3.4]Octane Hydrochloride
CAS No.	1956355-22-8
Molecular Formula	C7H14ClNO
Molecular Weight	163.65 g/mol
Synonyms	1-Oxa-6-azaspiro[3.4]octane hydrochloride; 1-Oxa-6-azaspiro[3.4]octane, hydrochloride; 6-Oxa-1-azaspiro[3.4]octane hydrochloride; Spiro[3.4]octane, 1-oxa-6-aza-, hydrochloride; 1956355-22-8; 1-Oxa-6-azaspiro[3.4]octane HCl
EINECS	Contact for details

Quality Control

Our production of 1-Oxa-6-Azaspiro[3.4]Octane Hydrochloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques. A Certificate of Analysis (COA) detailing the specific results for each lot is provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.