Description

N1,N2-Dimethylcyclohexane-1,2-Diamine Hydrochloride is a high-purity, chiral diamine derivative supplied as its hydrochloride salt, offering enhanced stability and handling properties. This compound serves as a critical chiral building block and ligand precursor in advanced organic synthesis, enabling the production of stereochemically defined molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise control over molecular architecture for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug candidates.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective hydrogenation, alkylation, and other C-C bond-forming reactions.
• Agrochemical Synthesis: Used in the development of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry impacts biological activity.
• Polymer Modification: Employed as a curing agent or chain extender in the production of specialty polyamides, polyurethanes, and epoxy resins to impart specific mechanical or thermal properties.
• Chelating Agent: Functions as a ligand for metal complexes in analytical chemistry, catalysis, and materials science.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and constructing complex molecular scaffolds.

Basic Information

Product Name	N1,N2-Dimethylcyclohexane-1,2-Diamine Hydrochloride
CAS No.	1956325-54-4
Molecular Formula	C8H20Cl2N2 (or C8H18N2 · 2HCl)
Molecular Weight	215.15 g/mol (Free base: 142.24 g/mol)
Synonyms	(1R,2R)-N1,N2-Dimethylcyclohexane-1,2-diamine dihydrochloride; (1S,2S)-N1,N2-Dimethylcyclohexane-1,2-diamine dihydrochloride; N,N'-Dimethyl-1,2-cyclohexanediamine hydrochloride; N,N'-Dimethyl-trans-1,2-diaminocyclohexane dihydrochloride; DACH Derivative; TMCDA·2HCl; Dimethyl-DACH·2HCl
EINECS	Contact for details

Quality Control

Our N1,N2-Dimethylcyclohexane-1,2-Diamine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (enantiomer excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.