Description

(6-Bromopyridin-2-Yl)Methanamine 2Hcl is a high-purity, dihydrochloride salt of a brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized, protected amine group adjacent to a halogenated aromatic system, enabling precise molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the pyridine scaffold is a core structural motif.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Scale-Up: A fundamental unit for contract research and manufacturing organizations (CROs/CMOs) performing custom synthesis from milligram to kilogram scale.
• Material Science: Potential monomer or functionalizing agent for creating specialized polymers and advanced organic materials.

Basic Information

Item	Details
Product Name	(6-Bromopyridin-2-Yl)Methanamine 2Hcl
CAS No.	1956309-87-7
Molecular Formula	C6H8BrN2·2HCl
Molecular Weight	284.41 g/mol (Free base: 187.05 g/mol)
Synonyms	1-(6-Bromopyridin-2-yl)methanamine dihydrochloride; (6-Bromo-2-pyridinyl)methanamine dihydrochloride; 2-(Aminomethyl)-6-bromopyridine dihydrochloride; 6-Bromo-2-pyridinemethanamine 2HCl; 6-Bromopyridin-2-ylmethylamine dihydrochloride; 2-Aminomethyl-6-bromopyridine hydrochloride (2:1); (6-Bromopyridin-2-yl)methylamine dihydrochloride
EINECS	Contact for details

Quality Control

Every batch of (6-Bromopyridin-2-Yl)Methanamine 2Hcl is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, which are designed to meet the exacting requirements of research and development as well as scale-up activities. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.