Description

4-Bromo-[1,5]Naphthyridine Dihydrobromide is a high-purity, halogenated naphthyridine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and pharmaceutical development, particularly in the creation of novel heterocyclic scaffolds. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce bromine functionality for further cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those targeting kinase inhibition.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage the naphthyridine core for bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology: Employed as a molecular probe or tag in bioconjugation and target identification studies due to its reactive bromine handle.
• Academic & Contract Research: A valuable reagent for methodology development in cross-coupling (e.g., Suzuki, Buchwald-Hartwig) and heterocyclic chemistry.
• Custom Synthesis: Used by fine chemical manufacturers for the bespoke production of complex molecules for client-specific projects.

Basic Information

Product Name	4-Bromo-[1,5]Naphthyridine Dihydrobromide
CAS No.	1956307-73-5
Molecular Formula	C8H6BrN2 · 2HBr
Molecular Weight	Contact for details
Synonyms	4-Bromo[1,5]naphthyridine dihydrobromide; [1,5]Naphthyridine, 4-bromo-, dihydrobromide; 4-Bromo-1,5-naphthyridine HBr salt; 4-Bromonaphthyridine hydrobromide salt; 4-Br-[1,5]Naphthyridine · 2HBr
EINECS	Contact for details

Quality Control

Our 4-Bromo-[1,5]Naphthyridine Dihydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.