Description

1,6-Diaza-Spiro[3.3]Heptane-6-Carboxylic Acid tert-Butyl Ester Hydrochloride (Wx100587S1) is a high-purity, protected spirocyclic diamine building block essential for modern pharmaceutical and agrochemical research. Its unique constrained spiro[3.3]heptane scaffold is highly valued for introducing three-dimensionality and improving the physicochemical properties of drug candidates. This compound is primarily utilized by medicinal chemists and process development scientists in the synthesis of novel active pharmaceutical ingredients (APIs) and advanced intermediates. The CAS number for this compound is 1955556-99-6.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of small molecule therapeutics targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• PROTAC & Molecular Glue Development: Used in constructing E3 ligase ligands and linkers for Proteolysis Targeting Chimeras (PROTACs) and other targeted protein degradation platforms.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides, fungicides, and insecticides, leveraging its spirocyclic structure for enhanced bioactivity and environmental profile.
• Peptidomimetics & Macrocycle Chemistry: Incorporated into peptide backbones to create rigid, metabolically stable analogs and to facilitate the cyclization of macrocyclic compounds.
• Chemical Biology Probes: Employed in the design and synthesis of tool compounds and probes for studying enzyme function and protein-protein interactions.
• Material Science: Potential monomer or cross-linking agent for advanced polymers with specific thermal or mechanical properties.

Basic Information

Item	Details
Product Name	1,6-Diaza-Spiro[3.3]Heptane-6-Carboxylic Acid tert-Butyl Ester Hydrochloride (Wx100587S1)
CAS No.	1955556-99-6
Molecular Formula	C11H21N2O2·HCl
Molecular Weight	264.76 g/mol
Synonyms	tert-Butyl 1,6-diazaspiro[3.3]heptane-6-carboxylate hydrochloride; 6-(tert-Butoxycarbonyl)-1,6-diazaspiro[3.3]heptane hydrochloride; 1,6-Diazaspiro[3.3]heptane-6-carboxylic acid, 1,1-dimethylethyl ester, hydrochloride; Boc-1,6-diazaspiro[3.3]heptane HCl; 1,6-Diazaspiro[3.3]heptane-6-carboxylate hydrochloride tert-butyl ester; Wx100587S1; 1955556-99-6
EINECS	Contact for details

Quality Control

Our 1,6-Diaza-Spiro[3.3]Heptane-6-Carboxylic Acid tert-Butyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and consistency for your sensitive chemistry applications.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and must be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. For long-term stability, store at 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with reference structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.