Description

6-Bromo-3,4-Dihydrospiro[1-Benzopyran-2,4''-Piperidine] Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel therapeutic agents. It is primarily sought after by pharmaceutical companies and contract research organizations (CROs) engaged in the discovery of central nervous system (CNS) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique spirocyclic scaffold.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Academic & Institutional R&D: Employed in university and institutional laboratories for fundamental research in organic synthesis and pharmacology.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries for high-throughput screening (HTS) in drug discovery.

Basic Information

Product Name	6-Bromo-3,4-Dihydrospiro[1-Benzopyran-2,4''-Piperidine] Hydrochloride
CAS No.	1955532-03-2
Molecular Formula	C14H17BrClNO
Molecular Weight	330.65 g/mol
Synonyms	6-Bromo-3,4-dihydrospiro[chromene-2,4'-piperidine] hydrochloride; 6-Bromospiro[chroman-2,4'-piperidine] hydrochloride; 6-Bromo-1,3-dihydrospiro[2H-1-benzopyran-2,4'-piperidine] hydrochloride; 6-Bromo-3,4-dihydro-2H-spiro[1-benzopyran-2,4'-piperidine] hydrochloride; 6-Bromo-3,4-dihydro-2H-1-benzopyran-2,4'-piperidine hydrochloride; 1955532-03-2; Spiro[chroman-2,4'-piperidine], 6-bromo-, hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Bromo-3,4-Dihydrospiro[1-Benzopyran-2,4''-Piperidine] Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.