Description

1-(5-Chloro-2-Fluorophenyl)Ethan-1-Amine Hydrochloride is a high-purity, pharmaceutically relevant organic salt, serving as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile chiral amine intermediate, enabling the synthesis of complex molecules with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the specific halogenated phenylamine structure contributes to biological activity.
• Chemical Research & Development: Serves as a fundamental building block in academic and industrial labs for exploring new synthetic pathways and methodologies.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for asymmetric catalysis and metal complexes.
• Fine Chemical Production: Incorporated into the manufacture of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	1-(5-Chloro-2-Fluorophenyl)Ethan-1-Amine Hydrochloride
CAS No.	1955523-20-2
Molecular Formula	C8H10Cl2FN
Molecular Weight	210.08 g/mol
Synonyms	1-(5-Chloro-2-fluorophenyl)ethanamine hydrochloride; (1R)-1-(5-Chloro-2-fluorophenyl)ethanamine hydrochloride (if chiral); α-Methyl-5-chloro-2-fluoro-benzenemethanamine hydrochloride; 5-Chloro-2-fluoro-α-methylbenzylamine hydrochloride; 1-Aminoethyl-5-chloro-2-fluorobenzene hydrochloride; (5-Chloro-2-fluorophenyl)ethylamine HCl; 1955523-20-2
EINECS	Contact for details

Quality Control

Our 1-(5-Chloro-2-Fluorophenyl)Ethan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.