Description

5-Fluoro-α-Methyl-2-Pyridinemethanamine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and building block. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific fluorinated pyridine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its fluorinated pyridine core, which can enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides, where the fluorine atom and pyridine structure contribute to biological activity.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis organizations (CSOs) and CDMOs producing specialized compounds for client projects.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	5-Fluoro-α-Methyl-2-Pyridinemethanamine Dihydrochloride
CAS No.	1955519-79-5
Molecular Formula	C8H12Cl2FN2
Molecular Weight	223.10 g/mol (Free base: C8H11FN2)
Synonyms	5-Fluoro-α-methyl-2-pyridinemethanamine dihydrochloride; 1-(5-Fluoropyridin-2-yl)ethan-1-amine dihydrochloride; 2-Pyridinemethanamine, 5-fluoro-α-methyl-, dihydrochloride; (1-(5-Fluoropyridin-2-yl)ethyl)amine dihydrochloride; 5-Fluoro-2-(1-aminoethyl)pyridine dihydrochloride; α-Methyl-5-fluoro-2-pyridinemethylamine dihydrochloride
EINECS	Contact for details

Quality Control

Our 5-Fluoro-α-Methyl-2-Pyridinemethanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.