Description

(1R,4S)-2-Azabicyclo[2.2.1]heptane Hydrochloride is a high-purity, chiral bicyclic amine hydrochloride salt, a key building block in advanced organic synthesis. This compound is valued for its rigid, three-dimensional scaffold which is instrumental in modulating the pharmacokinetic and pharmacodynamic properties of target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry for central nervous system (CNS) and antiviral drug discovery programs. CAS NO 1955474-63-1.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a constrained scaffold to explore structure-activity relationships (SAR) and improve metabolic stability and selectivity of lead compounds.
• Agrochemical Synthesis: Serves as a building block for developing new, more effective pesticides and herbicides with specific chiral activity.
• Catalyst and Ligand Development: Employed in the design and synthesis of novel chiral catalysts and ligands for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study biological pathways and enzyme functions.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic chemistry research.

Basic Information

Product Name	(1R,4S)-2-Azabicyclo[2.2.1]heptane Hydrochloride
CAS No.	1955474-63-1
Molecular Formula	C6H12ClN
Molecular Weight	133.62 g/mol
Synonyms	(1R,4S)-2-Azabicyclo[2.2.1]heptane HCl; endo-2-Azabicyclo[2.2.1]heptane Hydrochloride; (1R,4S)-2-Azanorbornane Hydrochloride; 2-Azabicyclo[2.2.1]heptane, hydrochloride, (1R,4S)-; endo-(1R,4S)-2-Azabicyclo[2.2.1]heptane hydrochloride; Bicyclo[2.2.1]heptan-2-amine, hydrochloride, (1R,4S)-; (1R,4S)-Bicyclo[2.2.1]hept-2-ylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (1R,4S)-2-Azabicyclo[2.2.1]heptane Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.