Description

(3S)-1-Phenylpyrrolidin-3-Amine Hydrochloride CAS NO 1955474-17-5 is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, process development, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and receptor-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to introduce the 1-phenylpyrrolidin-3-amine pharmacophore.
• Asymmetric Synthesis: Employed as a chiral amine source or auxiliary in catalytic and stoichiometric asymmetric transformations.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands and organocatalysts for fine chemical production.

Basic Information

Product Name	(3S)-1-Phenylpyrrolidin-3-Amine Hydrochloride
CAS No.	1955474-17-5
Molecular Formula	C10H15N2Cl
Molecular Weight	198.69 g/mol
Synonyms	(3S)-1-Phenyl-3-pyrrolidinamine hydrochloride; (S)-1-Phenylpyrrolidin-3-amine hydrochloride; (S)-3-Amino-1-phenylpyrrolidine hydrochloride; 1-Phenylpyrrolidin-3-amine hydrochloride, (3S)-; (S)-1-Phenyl-3-aminopyrrolidine HCl; (S)-N-Phenyl-3-aminopyrrolidine hydrochloride; (3S)-3-Amino-1-phenylpyrrolidine HCl
EINECS	Contact for details

Quality Control

Our (3S)-1-Phenylpyrrolidin-3-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and impurities is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.