Description

Ethyl 3-Acetamido-2-Oxo-1,2,3,4-Tetrahydroquinoline-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique tetrahydroquinoline core structure. This compound is critical for the synthesis of complex bioactive molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing novel therapeutic agents, particularly in the areas of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in the construction of complex heterocyclic compounds for academic and industrial research.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological processes and identify new therapeutic targets.

Basic Information

Product Name	Ethyl 3-Acetamido-2-Oxo-1,2,3,4-Tetrahydroquinoline-3-Carboxylate
CAS No.	1951441-35-2
Molecular Formula	C₁₄H₁₆N₂O₄
Molecular Weight	276.29 g/mol
Synonyms	Ethyl 3-acetamido-2-oxo-3,4-dihydro-1H-quinoline-3-carboxylate; 3-Carbethoxy-3-acetamido-1,2,3,4-tetrahydro-2-oxoquinoline; 1,2,3,4-Tetrahydro-2-oxo-3-quinolinecarboxylic acid, 3-(acetylamino)-, ethyl ester; Ethyl 3-(acetylamino)-1,2,3,4-tetrahydro-2-oxo-3-quinolinecarboxylate; 3-Acetamido-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylic acid ethyl ester; 1951441-35-2; Quinoline-3-carboxylic acid derivative.
EINECS	Contact for details

Quality Control

Our Ethyl 3-Acetamido-2-Oxo-1,2,3,4-Tetrahydroquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed batch-specific data are provided and can be tailored to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.