Description

Pyridin-3-Yl[4-(Trifluoromethyl)Phenyl]Methanamine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is valued for its precise molecular architecture, which is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and life science research sectors seeking to develop new therapeutic or crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a precursor for developing new-generation pesticides and herbicides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition, receptor binding, and other biochemical pathways.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of complex molecules.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers and advanced materials.

Basic Information

Product Name	Pyridin-3-Yl[4-(Trifluoromethyl)Phenyl]Methanamine Dihydrochloride
CAS No.	1951440-02-0
Molecular Formula	C13H12F3N2•2HCl
Molecular Weight	329.16 g/mol (Free base: 256.25 g/mol)
Synonyms	3-[(4-(Trifluoromethyl)phenyl]aminomethyl]pyridine dihydrochloride; [4-(Trifluoromethyl)phenyl](pyridin-3-yl)methanamine dihydrochloride; 1-[4-(Trifluoromethyl)phenyl]-1-(pyridin-3-yl)methanamine dihydrochloride; (Pyridin-3-yl)[4-(trifluoromethyl)phenyl]methanamine dihydrochloride; α-(3-Pyridyl)-4-(trifluoromethyl)benzylamine dihydrochloride; CAS 1951440-02-0
EINECS	Contact for details

Quality Control

Our Pyridin-3-Yl[4-(Trifluoromethyl)Phenyl]Methanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements for research and development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.