Description

3-(Trifluoromethyl)Quinoline-7-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its quinoline core and trifluoromethyl functionality. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring enhanced metabolic stability and bioavailability. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the quinoline scaffold.
• Material Science: Serves as a precursor for functionalized ligands and organic electronic materials due to its conjugated structure.
• Chemical Synthesis: Employed in organic chemistry research for the construction of complex heterocyclic compounds and fluorinated analogs.

Basic Information

Product Name	3-(Trifluoromethyl)Quinoline-7-Carboxylic Acid
CAS No.	1951439-59-0
Molecular Formula	C11H6F3NO2
Molecular Weight	241.17 g/mol
Synonyms	7-Quinolinecarboxylic acid, 3-(trifluoromethyl)-; 3-Trifluoromethylquinoline-7-carboxylic acid; 3-(Trifluoromethyl)-7-quinolinecarboxylic acid; Quinoline-7-carboxylic acid, 3-(trifluoromethyl)-; 1951439-59-0; 3-CF3-Quinoline-7-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Quinoline-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.