Description

Methyl Quinuclidine-2-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant building block and intermediate. This compound is valued for its rigid, bicyclic quinuclidine structure, which is instrumental in modulating the physicochemical and biological properties of target molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic applications.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Chemical Synthesis Building Block: Used to introduce the quinuclidine moiety into complex organic molecules for structure-activity relationship (SAR) studies.
• Medicinal Chemistry Research: Employed in the design and synthesis of compounds targeting neurological receptors and enzymes.
• Process Chemistry & Scale-up: Serves as a starting material for the optimization and production of advanced intermediates under GMP conditions.
• Academic Research: Used in universities and research institutes for methodological studies and novel reaction development.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and validation.

Basic Information

Product Name	Methyl Quinuclidine-2-Carboxylate Hydrochloride
CAS No.	1951438-80-4
Molecular Formula	C9H16ClNO2
Molecular Weight	205.68 g/mol
Synonyms	Methyl 2-quinuclidinecarboxylate hydrochloride; Quinuclidine-2-carboxylic acid methyl ester hydrochloride; Methyl quinuclidine-2-carboxylate HCl; 2-(Methoxycarbonyl)quinuclidine hydrochloride; 1-Azabicyclo[2.2.2]octane-2-carboxylic acid, methyl ester, hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl Quinuclidine-2-Carboxylate Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to support pharmaceutical development, with the capability to supply material that meets evolving project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.