Description

2-Benzyl-2,7-Diazaspiro[4.4]Nonane-1,3-Dione Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic diazepinedione scaffold. This compound is of significant commercial interest for its role as a key building block in the research and development of novel therapeutic agents, particularly within central nervous system (CNS) and metabolic disorder pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in innovative drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates targeting neurological receptors.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Bioconjugation & Probe Development: The reactive functional groups enable its use in creating biochemical probes for target identification and validation.
• Academic Research: Employed in university and institutional labs for studying spirocyclic compound chemistry and pharmacology.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up under cGMP conditions for clinical trial material production.

Basic Information

Product Name	2-Benzyl-2,7-Diazaspiro[4.4]Nonane-1,3-Dione Hydrochloride
CAS No.	1949836-83-2
Molecular Formula	C18H21N2O2•HCl
Molecular Weight	332.83 g/mol (Free base: 297.37 g/mol)
Synonyms	2-Benzyl-2,7-diazaspiro[4.4]nonane-1,3-dione hydrochloride; 2,7-Diazaspiro[4.4]nonane-1,3-dione, 2-benzyl-, hydrochloride; 2-Benzyl-2,7-diazaspiro[4.4]nonane-1,3-dione HCl; 1949836-83-2; UNII-8Q7H6J2V1F; 8Q7H6J2V1F; Spiro[diazepine-5,1'-cyclopentane] precursor; Benzyl diazaspiro nonanedione hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-Benzyl-2,7-Diazaspiro[4.4]Nonane-1,3-Dione Hydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting both research and development scale-up. A detailed Certificate of Analysis (COA) including results from HPLC, NMR, and mass spectrometry is supplied with each shipment to meet the stringent requirements of pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.