Description

2-Azabicyclo[2.2.1]Heptane-6-Carboxylic Acid Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique bridged bicyclic structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Organic Synthesis Building Block: Used in asymmetric synthesis and medicinal chemistry to construct complex molecular architectures due to its rigid bicyclic framework.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides with specific biological activity.
• Catalyst and Ligand Development: Potential use in the design of novel chiral catalysts and ligands for enantioselective transformations.
• Academic and R&D: Employed in university and corporate research laboratories for methodological studies and the exploration of new chemical entities.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Azabicyclo[2.2.1]Heptane-6-Carboxylic Acid Hydrochloride
CAS No.	1949816-37-8
Molecular Formula	C7H11NO2 • HCl
Molecular Weight	177.63 g/mol
Synonyms	6-Carboxy-2-azabicyclo[2.2.1]heptane hydrochloride; (1R,4S,6S)-6-Carboxy-2-azabicyclo[2.2.1]heptane hydrochloride; endo-6-Carboxy-2-azabicyclo[2.2.1]heptane HCl; 2-Azanorbornane-6-carboxylic acid hydrochloride; Bicyclo[2.2.1]heptane-6-carboxylic acid, 2-aza-, hydrochloride; 2-Azabicyclo[2.2.1]heptane-6-carboxylic acid HCl salt
EINECS	Contact for details

Quality Control

Our 2-Azabicyclo[2.2.1]Heptane-6-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identification by spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.