Description

tert-Butyl 3-Fluoro-4-Hydroxybenzylcarbamate is a high-purity, fluorinated carbamate derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom and carbamate group can enhance biological activity and stability.
• Peptide Mimetics & PROTACs: Serves as a versatile scaffold in the design of peptide analogs and Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.
• Material Science Precursor: Potential monomer or modifier in the synthesis of specialized polymers and advanced materials with unique properties.
• Chemical Biology Probes: Utilized in the creation of fluorescent tags, affinity labels, and other molecular probes for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	tert-Butyl 3-Fluoro-4-Hydroxybenzylcarbamate
CAS No.	1936257-24-7
Molecular Formula	C12H16FNO3
Molecular Weight	241.26 g/mol
Synonyms	Carbamic acid, N-[(3-fluoro-4-hydroxyphenyl)methyl]-, 1,1-dimethylethyl ester; tert-Butyl N-[(3-fluoro-4-hydroxyphenyl)methyl]carbamate; Boc-3-fluoro-4-hydroxybenzylamine; N-Boc-3-fluoro-4-hydroxybenzylamine; 3-Fluoro-4-hydroxybenzylcarbamic acid tert-butyl ester; tert-Butyl (3-fluoro-4-hydroxybenzyl)carbamate; N-(tert-Butoxycarbonyl)-3-fluoro-4-hydroxybenzylamine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Fluoro-4-Hydroxybenzylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. For advanced applications, we can supply material that meets research-grade or cGMP standards upon request, ensuring reliable integration into your sensitive synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.