Description

Benzoic Acid, 4-Bromo-3-(Fluorosulfonyl)- is a high-value, multi-functional aromatic building block characterized by its reactive bromo and fluorosulfonyl substituents. This compound is essential for facilitating complex molecular transformations in advanced synthetic chemistry, offering a unique combination of electrophilic and leaving group capabilities. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing sulfonamide or fluorine-containing pharmacophores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the bromo and fluorosulfonyl groups enable targeted bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl structures.
• Sulfonation & Sulfonamide Formation: The reactive fluorosulfonyl group is instrumental for introducing sulfonic acid derivatives or creating sulfonamide linkages under mild conditions.
• Chemical Biology & Proteomics: Employed as a tool compound or labeling reagent for modifying proteins, peptides, or other biomolecules due to its selective reactivity.

Basic Information

Product Name	Benzoic Acid, 4-Bromo-3-(Fluorosulfonyl)-
CAS No.	1935922-41-0
Molecular Formula	C7H4BrFO4S
Molecular Weight	279.07 g/mol
Synonyms	4-Bromo-3-(fluorosulfonyl)benzoic acid; 3-Fluorosulfonyl-4-bromobenzoic acid; 4-Bromo-3-fluorosulfonylbenzoic acid; Benzoic acid, 4-bromo-3-(fluorosulfonyl)-; 2-Bromo-5-carboxybenzenesulfonyl fluoride
EINECS	Contact for details

Quality Control

Our production of Benzoic Acid, 4-Bromo-3-(Fluorosulfonyl)- adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to support cGMP and ISO standards for research and commercial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.