Description

2-(Chloromethyl)-6-Fluoroquinazoline is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its unique molecular architecture, which combines a reactive chloromethyl handle with a fluorinated quinazoline core, enabling precise derivatization and the introduction of key pharmacophores. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other small-molecule drug candidates, leveraging the quinazoline scaffold's biological relevance.
• Agrochemical Research: Serves as a versatile building block for developing new herbicides and fungicides, where the fluorine atom can enhance bioavailability and stability.
• Material Science Chemistry: Used in the creation of specialized organic ligands and functional molecules for advanced materials, including OLEDs and sensors.
• Chemical Biology Probes: Employed to construct activity-based probes and labeled compounds for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects requiring complex, fluorinated heterocyclic structures.

Basic Information

Product Name	2-(Chloromethyl)-6-Fluoroquinazoline
CAS No.	1935241-50-1
Molecular Formula	C9H6ClFN2
Molecular Weight	196.61 g/mol
Synonyms	6-Fluoro-2-(chloromethyl)quinazoline; 2-(Chloromethyl)-6-fluoroquinazoline; Quinazoline, 2-(chloromethyl)-6-fluoro-; 1935241-50-1; 6-Fluoro-2-chloromethylquinazoline
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-6-Fluoroquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles ensures a reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.