Description

6-Bromo-4-Fluoro-1,3-Benzoxazole is a high-value halogenated benzoxazole derivative, a crucial building block in modern organic synthesis. Its core value lies in its dual functionalization, providing reactive handles for cross-coupling and nucleophilic substitution reactions essential for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides by serving as a core heterocyclic scaffold for bioactive molecules.
• Material Science: Acts as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the benzoxazole moiety into more complex structures.
• Fluorescent Probe Development: The benzoxazole core is utilized in the design and synthesis of fluorescent dyes and molecular probes for biochemical sensing and imaging.

Basic Information

Product Name	6-Bromo-4-Fluoro-1,3-Benzoxazole
CAS No.	1935181-98-8
Molecular Formula	C7H3BrFNO
Molecular Weight	215.01 g/mol
Synonyms	4-Fluoro-6-bromo-1,3-benzoxazole; 6-Bromo-4-fluorobenzoxazole; 1,3-Benzoxazole, 6-bromo-4-fluoro-; 4-Fluoro-6-bromobenzo[d]oxazole; 6-Br-4-F-Benzo[d]oxazole
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Fluoro-1,3-Benzoxazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC-MS, and NMR, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.