Description

2-Thiophenecarboxylic Acid, 5-Bromo-4-(Fluorosulfonyl)- is a high-value, multi-functional heterocyclic building block characterized by its reactive bromo and fluorosulfonyl substituents. This compound is essential for advanced organic synthesis, enabling the precise construction of complex molecules through selective cross-coupling and nucleophilic substitution reactions. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in developing kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection products, including herbicides and fungicides with novel modes of action.
• Material Science Research: Acts as a key monomer or functionalization agent in the development of conductive polymers, organic semiconductors, and specialty polymers.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of chemical probes to study biological systems.
• Ligand & Catalyst Development: Utilized in the design and synthesis of novel ligands for transition metal catalysis and organocatalysts.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Thiophenecarboxylic Acid, 5-Bromo-4-(Fluorosulfonyl)-
CAS No.	1934823-87-6
Molecular Formula	C6H2BrFO4S2
Molecular Weight	285.11 g/mol
Synonyms	5-Bromo-4-(fluorosulfonyl)thiophene-2-carboxylic acid; 4-Fluorosulfonyl-5-bromothiophene-2-carboxylic acid; 5-Bromo-4-fluorosulfonyl-2-thiophenecarboxylic acid; 2-Thiophenecarboxylic acid, 5-bromo-4-(fluorosulfonyl)-; 1934823-87-6; 5-Bromo-4-fluorosulfonylthiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarboxylic Acid, 5-Bromo-4-(Fluorosulfonyl)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.