Description

Racemic-(6R,7S)-tert-Butyl 7-Amino-1-Oxa-4-Azaspiro[5.5]Undecane-4-Carboxylate (Wx102155) is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated chiral and heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes for potential APIs under Good Manufacturing Practice (GMP) conditions.
• Spirocyclic Compound Library Synthesis: Utilized in combinatorial chemistry and high-throughput screening to create diverse libraries of spiro-fused heterocycles for biological evaluation.
• Asymmetric Synthesis: The racemic mixture provides a foundation for chiral resolution studies or serves as a precursor for developing enantioselective synthetic pathways.

Basic Information

Product Name	Racemic-(6R,7S)-tert-Butyl 7-Amino-1-Oxa-4-Azaspiro[5.5]Undecane-4-Carboxylate (Wx102155)
CAS No.	1932808-85-9
Molecular Formula	C14H26N2O3
Molecular Weight	270.37 g/mol
Synonyms	tert-Butyl 7-amino-1-oxa-4-azaspiro[5.5]undecane-4-carboxylate; (±)-(6R,7S)-tert-Butyl 7-Amino-1-Oxa-4-Azaspiro[5.5]Undecane-4-Carboxylate; 4-Azaspiro[5.5]undecane-4-carboxylic acid, 7-amino-1-oxa-, 1,1-dimethylethyl ester, (6R,7S)-rel-; WX-102155; Wx102155; 1-Oxa-4-azaspiro[5.5]undecane-4-carboxylic acid, 7-amino-, 1,1-dimethylethyl ester, (6R,7S)-rel-; BOC-protected 7-amino-1-oxa-4-azaspiro[5.5]undecane
EINECS	Contact for details

Quality Control

Our Racemic-(6R,7S)-tert-Butyl 7-Amino-1-Oxa-4-Azaspiro[5.5]Undecane-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation from moisture uptake. For long-term storage, consider storing desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.