Description

(R)-2-((1S,4S)-4-(6-Fluoroquinolin-4-Yl)Cyclohexyl)Propanoic Acid is a high-purity, chiral pharmaceutical intermediate of significant importance in modern drug discovery and development. Its precise stereochemistry and fluorinated quinoline core make it a valuable building block for synthesizing targeted therapeutic agents. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel small-molecule drugs, particularly in areas requiring specific three-dimensional molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Drug Discovery: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Protease Inhibitor Research: Serves as a potential precursor or core structure in the synthesis of enzyme inhibitors.
• Chemical Biology Probes: Utilized in the creation of labeled or tagged molecules for studying biological pathways.
• Asymmetric Synthesis: Employed as a starting material or intermediate in stereoselective chemical reactions.
• Preclinical Development: Supplied for the synthesis of compounds used in pharmacological and toxicological testing.

Basic Information

Product Name	(R)-2-((1S,4S)-4-(6-Fluoroquinolin-4-Yl)Cyclohexyl)Propanoic Acid
CAS No.	1923836-34-3
Molecular Formula	C18H20FNO2
Molecular Weight	301.36 g/mol
Synonyms	(1R,2S,5S)-2-(6-Fluoro-4-quinolyl)-5-methylcyclohexanecarboxylic Acid; (R)-2-[(1S,4S)-4-(6-Fluoro-4-quinolyl)cyclohexyl]propanoic Acid; 1923836-34-3; UNII-8H6SXB5V8I; 8H6SXB5V8I; (1R,2S,5S)-5-Methyl-2-(6-fluoroquinolin-4-yl)cyclohexane-1-carboxylic acid; (1R,2S,5S)-rel-2-(6-Fluoro-4-quinolyl)-5-methylcyclohexanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our (R)-2-((1S,4S)-4-(6-Fluoroquinolin-4-Yl)Cyclohexyl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by advanced techniques like HPLC and NMR, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.