Description

(S)-1-(2-Methoxypyridin-4-Yl)Ethanamine Hydrochloride is a high-purity chiral amine building block of significant importance in modern pharmaceutical research and development. Its defined stereochemistry and functionalized pyridine core make it a valuable intermediate for constructing complex, biologically active molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in drug discovery and the synthesis of advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Ligand and Catalyst Precursor: Used in the development of asymmetric catalysts and chiral ligands for enantioselective synthesis.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and insecticides requiring specific stereochemistry for efficacy.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and receptor interactions.
• Peptidomimetics: Incorporated into peptide analogs to enhance stability, bioavailability, and target specificity.
• Material Science: Potential monomer or functionalization agent for advanced polymers and chiral stationary phases (CSPs) in chromatography.

Basic Information

Product Name	(S)-1-(2-Methoxypyridin-4-Yl)Ethanamine Hydrochloride
CAS No.	1914157-93-9
Molecular Formula	C8H13ClN2O
Molecular Weight	188.65 g/mol
Synonyms	(S)-1-(2-Methoxypyridin-4-yl)ethan-1-amine hydrochloride; (S)-1-(2-Methoxy-4-pyridinyl)ethylamine hydrochloride; (S)-α-Methyl-2-methoxy-4-pyridineethanamine hydrochloride; (S)-4-(1-Aminoethyl)-2-methoxypyridine hydrochloride; 2-Methoxy-4-[(1S)-1-aminoethyl]pyridine hydrochloride; (S)-2-Methoxy-4-(1-aminoethyl)pyridine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-1-(2-Methoxypyridin-4-Yl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.