Description

(R)-1-(2-Methoxypyridin-4-Yl)Ethanamine Dihydrochloride is a high-purity chiral amine building block essential for advanced pharmaceutical synthesis. This compound is a critical intermediate in the development of targeted active pharmaceutical ingredients (APIs), particularly for chiral drugs requiring specific stereochemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and production of novel therapeutics, including kinase inhibitors and other small molecule drugs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex, stereospecific Active Pharmaceutical Ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for the design and optimization of lead compounds, especially in oncology and CNS drug development.
• Asymmetric Synthesis: Serves as a chiral amine precursor in catalytic asymmetric reactions to construct molecules with high enantiomeric purity.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and biological pathways.
• Process Chemistry Development: Used for scaling up synthetic routes from laboratory to pilot and commercial manufacturing scales.

Basic Information

Product Name	(R)-1-(2-Methoxypyridin-4-Yl)Ethanamine Dihydrochloride
CAS No.	1914157-92-8
Molecular Formula	C8H14Cl2N2O
Molecular Weight	225.11 g/mol
Synonyms	(R)-1-(2-Methoxypyridin-4-yl)ethan-1-amine dihydrochloride; (R)-1-(2-Methoxy-4-pyridinyl)ethylamine dihydrochloride; (R)-1-(2-Methoxypyridin-4-yl)ethylamine dihydrochloride; (R)-4-(1-Aminoethyl)-2-methoxypyridine dihydrochloride; (R)-α-Methyl-2-methoxy-4-pyridineethanamine dihydrochloride; (R)-2-Methoxy-4-(1-aminoethyl)pyridine dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(2-Methoxypyridin-4-Yl)Ethanamine Dihydrochloride is manufactured under strict quality systems suitable for pharmaceutical research and development. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.