Description

3,9-Diazaspiro[5.5]Undecan-2-One 2,2,2-Trifluoroacetate is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic diaza structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex, bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the fields of neurology and oncology.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting G-protein-coupled receptors (GPCRs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and process development stages for potential new APIs requiring a rigid, nitrogen-containing bicyclic framework.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	3,9-Diazaspiro[5.5]Undecan-2-One 2,2,2-Trifluoroacetate
CAS No.	1914148-54-1
Molecular Formula	C12H18F3N3O3
Molecular Weight	309.28 g/mol
Synonyms	3,9-Diazaspiro[5.5]undecan-2-one trifluoroacetate; 2-Oxo-3,9-diazaspiro[5.5]undecane trifluoroacetate; 3,9-Diazaspiro[5.5]undecan-2-one TFA salt; Spirocyclic diaza lactam TFA salt; 3,9-Diazaspiro[5.5]undecane-2-one trifluoroacetic acid salt
EINECS	Contact for details

Quality Control

Our 3,9-Diazaspiro[5.5]Undecan-2-One 2,2,2-Trifluoroacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.