Description

4-Azaspiro[2.5]Octan-7-Ol Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic amine structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) therapeutics, antiviral agents, and other complex small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a constrained scaffold to explore structure-activity relationships (SAR) and improve the pharmacokinetic properties of lead compounds.
• API Synthesis: Serves as a critical building block in multi-step synthetic routes for producing complex target molecules in pre-clinical and clinical development.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.

Basic Information

Product Name	4-Azaspiro[2.5]Octan-7-Ol Hydrochloride
CAS No.	1909347-89-2
Molecular Formula	C7H14ClNO
Molecular Weight	163.65 g/mol
Synonyms	7-Hydroxy-4-azaspiro[2.5]octane hydrochloride; 4-Azaspiro[2.5]octan-7-ol, hydrochloride; 4-Azaspiro[2.5]octan-7-ol HCl; 7-Hydroxy-1-azaspiro[2.5]octane hydrochloride; Spirocyclic amine hydrochloride intermediate
EINECS	Contact for details

Quality Control

Our 4-Azaspiro[2.5]Octan-7-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.