Description

tert-Butyl n-(1-Carbamimidoyl-1-Methylethyl)Carbamate is a high-purity, protected guanidine derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in enabling the controlled introduction of the guanidine functional group, a key pharmacophore in medicinal chemistry, under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly protease inhibitors and other biologically active molecules. The CAS number for this specific compound is 1909326-26-6.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of protease inhibitors, kinase inhibitors, and other drug candidates containing guanidine motifs.
• Peptidomimetic Research: Used in the design and construction of peptide analogs where the guanidine group mimics arginine side chains for enhanced binding affinity and metabolic stability.
• Agrochemical Development: Serves as a building block for novel herbicides, fungicides, and insecticides that leverage the bioactivity of guanidine derivatives.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and activity-based probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & R&D: Used in university and institutional laboratories for fundamental research in organic methodology and medicinal chemistry.

Basic Information

Item	Details
Product Name	tert-Butyl n-(1-Carbamimidoyl-1-Methylethyl)Carbamate
CAS No.	1909326-26-6
Molecular Formula	C10H19N3O2
Molecular Weight	213.28 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-2-methyl-2-propaneimidamide; 2-Methyl-2-[(tert-butoxycarbonyl)amino]propanimidamide; Boc-protected 2-methyl-2-aminopropanimidamide; tert-Butyl (1-carbamimidoyl-1-methylethyl)carbamate; (1-Carbamimidoyl-1-methylethyl)-carbamic acid tert-butyl ester; BOC-2-methylalanine amidine; Guanidine derivative, BOC-protected
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(1-Carbamimidoyl-1-Methylethyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.