Description

5-Oxaspiro[3.4]Octan-7-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic oxa-ketone structure. This compound matters as a critical building block in modern organic synthesis, enabling the construction of complex molecular architectures with high stereochemical control. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging its spirocyclic scaffold for novel modes of action.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and mechanical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in spirocyclic and heterocyclic chemistry.
• Ligand and Catalyst Development: The oxa-spiro structure can be functionalized to create novel chiral ligands for asymmetric catalysis.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing musk-like or other complex odorant molecules due to its constrained bicyclic framework.

Basic Information

Product Name	5-Oxaspiro[3.4]Octan-7-One
CAS No.	1909305-22-1
Molecular Formula	C7H10O2
Molecular Weight	126.15 g/mol
Synonyms	5-Oxaspiro[3.4]octan-7-one; 7-Oxaspiro[3.4]octan-5-one; Spiro[3.4]octan-7-one, 5-oxa-; Tetrahydro-4H-furo[3,4-c]oxet-4-one; 4H-Furo[3,4-c]oxet-4-one, tetrahydro-; Oxaspirooctanone; 1909305-22-1
EINECS	Contact for details

Quality Control

Our 5-Oxaspiro[3.4]Octan-7-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.