Description

cis-3-(Propan-2-Yloxy)Cyclobutan-1-Amine Hydrochloride is a high-purity, synthetically valuable chiral amine hydrochloride salt, serving as a critical building block in modern organic synthesis. Its primary value lies in providing a rigid, functionalized cyclobutane scaffold, which is essential for constructing complex molecules with specific three-dimensional architectures. This compound is particularly sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, process development, and the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of new drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclobutane ring can confer unique biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereochemistry.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specialized thermal or mechanical properties.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	cis-3-(Propan-2-Yloxy)Cyclobutan-1-Amine Hydrochloride
CAS No.	1909294-44-5
Molecular Formula	C7H16ClNO
Molecular Weight	165.66 g/mol
Synonyms	cis-3-Isopropoxycyclobutan-1-amine hydrochloride; (1s,3s)-3-(Propan-2-yloxy)cyclobutan-1-amine hydrochloride; 3-Isopropoxycyclobutan-1-amine hydrochloride (cis-); 1-Cyclobutanamine, 3-[(1-methylethyl)oxy]-, hydrochloride, (1s,3s)-; cis-3-(Isopropyloxy)cyclobutanamine hydrochloride; (1s,3s)-3-Isopropoxycyclobutan-1-amine HCl; 1909294-44-5
EINECS	Contact for details

Quality Control

Every batch of cis-3-(Propan-2-Yloxy)Cyclobutan-1-Amine Hydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive R&D and scale-up applications. A detailed Certificate of Analysis (COA) including chiral purity, assay, and impurity profile is supplied with each shipment. Our quality commitment supports compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual unknown ≤0.10%, Total ≤0.50%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.