Description

4-Fluorotetrahydrofuran-3-Amine Hydrochloride (Wxc04480) is a high-purity, advanced pharmaceutical intermediate with the CAS number 1903830-44-3. This compound is a critical building block in modern medicinal chemistry, valued for its unique fluorinated tetrahydrofuran scaffold which can significantly influence the metabolic stability and bioavailability of target molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapies.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to introduce fluorine atoms and amine functionalities into lead compounds.
• API Development: Serves as a crucial precursor in the multi-step manufacturing process of Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of labeled compounds and probes for studying biological mechanisms.
• Agrochemical Research: Potential application as an intermediate in the development of novel, high-performance crop protection agents.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for exploratory synthetic chemistry.

Basic Information

Product Name	4-Fluorotetrahydrofuran-3-Amine Hydrochloride (Wxc04480)
CAS No.	1903830-44-3
Molecular Formula	C4H9FNO•HCl
Molecular Weight	153.59 g/mol
Synonyms	3-Amino-4-fluorotetrahydrofuran hydrochloride; 4-Fluoro-3-aminotetrahydrofuran HCl; 4-Fluoro-3-tetrahydrofuranamine hydrochloride; 3-Amino-4-fluorotetrahydrofuran HCl salt; 4-Fluoro-3-aminotetrahydrofuran hydrochloride; WXC-04480; Wxc04480; 1903830-44-3
EINECS	Contact for details

Quality Control

Our 4-Fluorotetrahydrofuran-3-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.