Description

(3R,4R)-3-Fluorooxan-4-Amine Hcl is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a defined stereochemical center and fluorine atom, enabling the development of novel compounds with enhanced biological activity and metabolic stability. This intermediate is essential for research and production in the pharmaceutical industry, particularly for medicinal chemists developing new active pharmaceutical ingredients (APIs) and agrochemical scientists creating next-generation crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of fluorinated drug candidates, including potential antiviral, antibacterial, and central nervous system (CNS) agents.
• Agrochemical Research: Used in the development of novel fluorinated pesticides and herbicides, where the fluorine atom can improve lipophilicity and target binding.
• Organofluorine Chemistry: Serves as a versatile precursor for introducing both amine and fluorine functionalities into complex molecular architectures.
• Asymmetric Synthesis: Employed as a chiral auxiliary or resolving agent in stereoselective reactions to produce enantiomerically pure compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	(3R,4R)-3-Fluorooxan-4-Amine Hcl
CAS No.	1895912-86-3
Molecular Formula	C5H11ClFNO
Molecular Weight	155.60 g/mol
Synonyms	(3R,4R)-3-Fluorooxan-4-amine hydrochloride; (3R,4R)-3-Fluorotetrahydro-2H-pyran-4-amine HCl; 4-Amino-3-fluorotetrahydropyran hydrochloride (3R,4R)-; (3R,4R)-3-Fluoro-4-aminotetrahydropyran hydrochloride; (3R,4R)-4-Amino-3-fluorotetrahydropyran hydrochloride; (3R,4R)-3-Fluoro-4-aminotetrahydro-2H-pyran hydrochloride; (3R,4R)-3-Fluoro-4-aminotetrahydropyran HCl
EINECS	Contact for details

Quality Control

Every batch of (3R,4R)-3-Fluorooxan-4-Amine Hcl is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.