Description

Spiro[Imidazolidine-4,1'-[1H]Indene]-2,3',5(2'H)-Trione, 5'-Bromo-, (1'S)- is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic and brominated indene structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting complex disease pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those with spirocyclic architectures.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• API Development: Serves as a precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme inhibition and biological pathways.
• Asymmetric Synthesis: The chiral (1'S) configuration makes it valuable for synthesizing enantiomerically pure compounds.
• Academic & Industrial R&D: Employed in research institutions and corporate R&D centers for exploratory chemistry and new molecule design.

Basic Information

Product Name	Spiro[Imidazolidine-4,1'-[1H]Indene]-2,3',5(2'H)-Trione, 5'-Bromo-, (1'S)-
CAS No.	1889290-55-4
Molecular Formula	C12H7BrN2O3
Molecular Weight	307.10 g/mol
Synonyms	(1'S)-5'-Bromospiro[imidazolidine-4,1'-[1H]indene]-2,3',5(2'H)-trione; 5'-Bromo-(1'S)-spiro[imidazolidine-4,1'-[1H]indene]-2,3',5(2'H)-trione; (1'S)-5'-Bromo-1'H-spiro[imidazolidine-4,1'-indene]-2,3',5(2'H)-trione; 1889290-55-4; Spiroimidazolidine-indene-trione bromo derivative; Bromo-spirocyclic imidazolidine trione
EINECS	Contact for details

Quality Control

Our Spiro[Imidazolidine-4,1'-[1H]Indene]-2,3',5(2'H)-Trione, 5'-Bromo-, (1'S)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.