Description

5''-Bromospiro[Imidazolidine-4,1''-[1H]Indene]-2,3'',5(2''H)-Trione is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic and brominated indene structure. This compound is of significant value in modern organic synthesis, serving as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and complex heterocyclic molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, process R&D, and the synthesis of new chemical entities targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with spirocyclic or fused heterocyclic scaffolds.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Reagent: Employed in advanced organic reactions, including cross-coupling and cyclization, to construct complex molecular architectures.
• Agrochemical Development: Potential application as an intermediate in the synthesis of new agrochemicals with specific biological activities.
• Material Science Research: Investigated for the development of organic electronic materials or specialty polymers due to its rigid, functionalized structure.

Basic Information

Product Name	5''-Bromospiro[Imidazolidine-4,1''-[1H]Indene]-2,3'',5(2''H)-Trione
CAS No.	1889290-24-7
Molecular Formula	C11H7BrN2O3
Molecular Weight	295.09 g/mol
Synonyms	5'-Bromospiro[imidazolidine-4,1'-[1H]indene]-2,3',5(2'H)-trione; 5-Bromospiro[imidazolidine-4,1-indene]-2,3,5-trione; Spiro[imidazolidine-4,1-indene]-2,3,5-trione, 5-bromo-; 1889290-24-7; 5-Bromo-spiro[imidazolidine-4,1'-indene]-2,3',5'-trione
EINECS	Contact for details

Quality Control

Our 5''-Bromospiro[Imidazolidine-4,1''-[1H]Indene]-2,3'',5(2''H)-Trione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.