Description

6-Aza-Spiro[4.5]Decane Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic amine structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research. It is primarily sought by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of potential drug candidates targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• API Development: Serves as a precursor in the multi-step synthesis of complex molecules for preclinical and clinical trials.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying enzyme and receptor function.
• Academic Research: Employed in universities and research institutes for exploratory synthetic chemistry and novel heterocycle development.

Basic Information

Product Name	6-Aza-Spiro[4.5]Decane Hydrochloride
CAS No.	1888784-60-8
Molecular Formula	C9H18ClN
Molecular Weight	175.70 g/mol
Synonyms	6-Azaspiro[4.5]decane hydrochloride; 1-Azaspiro[4.5]decane hydrochloride (common numbering); 1-Aza-spiro[4.5]decane HCl; Spiro[4.5]decan-6-amine hydrochloride; Azaspirodecane hydrochloride; 6-Aza-spiro[4,5]decane HCl; 1888784-60-8; 6-Aza-spiro[4.5]decane, hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Aza-Spiro[4.5]Decane Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.