Description

3-Chlorobicyclo[1.1.1]pentan-1-amine hydrochloride is a high-purity, synthetically valuable bicyclic amine derivative, offered as a stable hydrochloride salt. This compound serves as a crucial advanced pharmaceutical intermediate and a versatile molecular scaffold for medicinal chemistry and materials science research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel bioactive molecules and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of central nervous system (CNS) and metabolic disorder therapeutics.
• Medicinal Chemistry Scaffold: Used in fragment-based drug discovery and lead optimization to explore novel chemical space due to its unique, rigid [1.1.1]propellane-derived structure.
• Agrochemical Research: Intermediate in the development of new-generation herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Synthesis: Precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Polymer & Material Science: Monomer or cross-linking agent for producing high-performance polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Used to synthesize molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	3-Chlorobicyclo[1.1.1]pentan-1-amine Hydrochloride
CAS No.	1886967-25-4
Molecular Formula	C5H9Cl2N
Molecular Weight	154.04 g/mol
Synonyms	3-Chloro-1-aminobicyclo[1.1.1]pentane hydrochloride; 1-Amino-3-chlorobicyclo[1.1.1]pentane hydrochloride; 3-Chlorobicyclo[1.1.1]pentan-1-amine HCl; Bicyclo[1.1.1]pentan-1-amine, 3-chloro-, hydrochloride; 3-Chloro-BCP-amine HCl; 3-Cl-BCP-NH2·HCl
EINECS	Contact for details

Quality Control

Our 3-Chlorobicyclo[1.1.1]pentan-1-amine hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.